QRSL1 and KRT8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		QRSL1	KRT8
Description		glutaminyl-tRNA amidotransferase subunit QRSL1	keratin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Glutamyl-tRNA(Gln) Amidotransferase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding
	Biological Process	Regulation Of Protein Stability Mitochondrial Translation Glutaminyl-tRNAGln Biosynthesis Via Transamidation	Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways			Keratinization Formation of the cornified envelope
Drugs			Tenecteplase Lanoteplase Copper
Diseases
GWAS		Clostridioides difficle infection in antibiotics-users ( 33841421) Daytime sleep phenotypes ( 27126917)	Alanine aminotransferase levels ( 33547301 34315874 33339817) Aspartate aminotransferase levels ( 33547301 34315874) Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Opioid dependence (time to event) ( 34124712) Prostate cancer ( 21743057) Sick sinus syndrome ( 33580673)
Interacting Genes		3 interacting genes: KRT8 OGT XRCC6	50 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 OGT PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2
Entrez ID		55278	3856
HPRD ID		15199	01015
Ensembl ID		ENSG00000130348	ENSG00000170421
Uniprot IDs		Q9H0R6	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?
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