KRT8 and KRT28

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRT8	KRT28
Description		keratin 8	keratin 28
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Biological_process
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Lanoteplase Copper
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874 33339817) Aspartate aminotransferase levels ( 33547301 34315874) Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Opioid dependence (time to event) ( 34124712) Prostate cancer ( 21743057) Sick sinus syndrome ( 33580673)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Glucose homeostasis traits ( 25524916)
Interacting Genes		50 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 OGT PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2	19 interacting genes: ABI3 CCDC196 DEUP1 KRT1 KRT3 KRT4 KRT5 KRT6A KRT6B KRT71 KRT79 KRT8 KRT80 KRT81 KRT86 NUP58 UCHL5 USHBP1 WASHC1
Entrez ID		3856	162605
HPRD ID		01015	17245
Ensembl ID		ENSG00000170421	ENSG00000173908
Uniprot IDs		P05787 Q7L4M3	Q7Z3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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