KRT8 and QRSL1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		KRT8	QRSL1
Description		keratin 8	glutaminyl-tRNA amidotransferase subunit QRSL1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Mitochondrion Glutamyl-tRNA(Gln) Amidotransferase Complex
	Molecular Function	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding	Protein Binding ATP Binding Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity
	Biological Process	Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Regulation Of Protein Stability Mitochondrial Translation Glutaminyl-tRNAGln Biosynthesis Via Transamidation
Pathways		Keratinization Formation of the cornified envelope
Drugs		Tenecteplase Lanoteplase Copper
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874 33339817) Aspartate aminotransferase levels ( 33547301 34315874) Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Mean reticulocyte volume ( 32888494) Opioid dependence (time to event) ( 34124712) Prostate cancer ( 21743057) Sick sinus syndrome ( 33580673)	Clostridioides difficle infection in antibiotics-users ( 33841421) Daytime sleep phenotypes ( 27126917)
Interacting Genes		50 interacting genes: ANXA1 BYSL CEP57 CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT16 KRT18 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT38 KRT40 LINC01554 MAPK1 MAPK14 MAPK3 MAPK8 NEK6 OGT PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 SUMO2 TCHP TFIP11 TRIM54 TROAP WBP2	3 interacting genes: KRT8 OGT XRCC6
Entrez ID		3856	55278
HPRD ID		01015	15199
Ensembl ID		ENSG00000170421	ENSG00000130348
Uniprot IDs		P05787 Q7L4M3	Q9H0R6
PDB IDs
Enriched GO Terms of Interacting Partners?
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