CHCHD3 and CALCOCO2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CHCHD3	CALCOCO2
Description		coiled-coil-helix-coiled-coil-helix domain containing 3	calcium binding and coiled-coil domain 2
Image		No pdb structure
GO Annotations	Cellular Component	SAM Complex Nucleus Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome MIB Complex	Autophagosome Membrane Nucleus Cytoplasm Autophagosome Cytosol Cytoskeleton Membrane PML Body Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phosphatase Binding Molecular Adaptor Activity	Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Viral Process Response To Interferon-gamma Xenophagy Positive Regulation Of Autophagosome Maturation
Pathways		Mitochondrial protein import Cristae formation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)	Blood protein levels ( 30072576) Chronotype ( 30696823) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 29358691 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		40 interacting genes: AASS AMOTL2 ANKS1A ARMC7 BLZF1 C2CD6 CALCOCO2 CBY2 CCDC33 CCDC85B CEP72 CLPP CYSRT1 DGKI EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1	183 interacting genes: ABLIM1 ADSL AKAP17A AMMECR1 AP5B1 APEX2 ARHGEF39 ARHGEF5 ARNT2 ATG5 AXIN1 BAHD1 BCL6B BEX2 CBX8 CCDC120 CCDC185 CCDC33 CCNH CDC7 CELA2B CEP57L1 CHCHD3 CNNM3 CPNE7 CWF19L2 DAXX DAZAP2 DBNDD2 DCTN4 DCX DDIT4L DDX6 DOCK2 DUSP12 DUSP26 EEF1E1 EFHC1 ELOA2 ENKD1 EXOSC5 FAM107A FAM161A FAM168A FAM189A2 FAM214B FAM90A1 FARS2 FASTK FBF1 FBXL18 FKBPL FMR1 FNDC11 FOXD4L3 FXR2 GABARAPL1 GABARAPL2 GATAD2B GCA GEMIN4 GIT2 GLYCTK HDAC4 HDAC7 HLX HNRNPLL HOXB5 HOXB9 IKBKG IL16 IQUB KANSL1 KAT7 KLHL35 KLHL42 LENG1 LGALS8 LGALS9 LIMS2 LITAF LMF2 LMO2 LMO4 LNX1 LONRF1 LSM4 MAGOHB MAP1LC3C MCM10 METTL17 MID2 MOS MTPAP MVP MXI1 MYH6 MYO6 NAA10 NDN NFU1 ORC5 PCGF1 PEF1 PEG10 PFDN5 PHF1 PIAS4 PLEKHN1 POLI POLR2A PPP1R18 PRKAA2 PRKAB2 PRPF18 PRPF31 PSMA1 PSME4 PTBP1 PTBP2 QARS1 RAB35 RABL6 RBM15 RHPN1 RIN1 RNF11 RPA2 RPL9 RPS27A RTN4IP1 RTP5 RXRB SCAND1 SCNM1 SDCBP SETD5 SHC1 SLC15A3 SMARCD1 SMCP SNRPB SPATA24 SRI STAMBPL1 STK16 TACO1 TBC1D22B TBK1 TBKBP1 TBRG4 TCL1A TEKT3 TENT2 TLE5 TP53RK TRAF2 TRAF4 TRAF6 TSC1 TSGA10IP TTC23L UBAC2 USP2 VARS1 VPS72 ZBTB4 ZC2HC1C ZNF101 ZNF205 ZNF337 ZNF408 ZNF414 ZNF426 ZNF451 ZNF564 ZNF581 ZNF638 ZNF648 ZNF688 ZNF696 ZNF774 ZNF80
Entrez ID		54927	10241
HPRD ID		13044	06846
Ensembl ID		ENSG00000106554	ENSG00000136436
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	Q13137
PDB IDs			2MXP 3VVV 3VVW 4GXL 4HAN 4XKL 5AAQ 5Z7A 5Z7L
Enriched GO Terms of Interacting Partners?
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