TRIT1 and COL6A3

		TRIT1	COL6A3
Description		tRNA isopentenyltransferase 1	collagen type VI alpha 3 chain
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Collagen Type VI Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Nucleic Acid Binding ATP Binding Zinc Ion Binding TRNA Dimethylallyltransferase Activity	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	TRNA Modification Mitochondrial TRNA Modification	Cell Adhesion Muscle Organ Development Negative Regulation Of Endopeptidase Activity
Pathways		tRNA modification in the nucleus and cytosol tRNA modification in the mitochondrion	Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Abstraction and mental flexibility ( 31596458) Aging (time to event) ( 21782286) Chronic kidney disease ( 30226566) Coronary artery disease ( 29212778 30402224 33020668) Cortex volume ( 31530798) HDL cholesterol ( 26160806) Heel bone mineral density ( 30598549) Height ( 33713608) Hypertension ( 30226566) Intraocular pressure ( 29617998 29235454) Ischemic stroke ( 29930801) LDL cholesterol ( 26160806) Lung cancer ( 28604730) Myocardial infarction ( 30226566) Pulse pressure ( 27841878)
Interacting Genes		6 interacting genes: ANKS1A COL6A3 HGH1 OGT SHE SMYD3	12 interacting genes: ALPG CDT1 DYSF GBX2 GFRA3 KCNJ13 MMP2 NGFR PPT1 SEPTIN2 SUDS3 TRIT1
Entrez ID		54802	1293
HPRD ID		18226	00371
Ensembl ID		ENSG00000043514	ENSG00000163359
Uniprot IDs		Q3T7C7 Q53F11 Q9H3H1	B7ZW00 D9ZGF2 P12111 Q63HQ4 Q8N4Z1
PDB IDs			1KNT 1KTH 1KUN 2KNT 6SNK
Enriched GO Terms of Interacting Partners?
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