COL6A3 and SUDS3

		COL6A3	SUDS3
Description		collagen type VI alpha 3 chain	SDS3 homolog, SIN3A corepressor complex component
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type VI Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Cytosol Sin3 Complex Nuclear Body Sin3-type Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Conferring Tensile Strength	Histone Deacetylase Activity Protein Binding Enzyme Binding Histone Deacetylase Binding
	Biological Process	Cell Adhesion Muscle Organ Development Negative Regulation Of Endopeptidase Activity	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Substantia Nigra Development Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization	HDACs deacetylate histones NoRC negatively regulates rRNA expression Ub-specific processing proteases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Aging (time to event) ( 21782286) Chronic kidney disease ( 30226566) Coronary artery disease ( 29212778 30402224 33020668) Cortex volume ( 31530798) HDL cholesterol ( 26160806) Heel bone mineral density ( 30598549) Height ( 33713608) Hypertension ( 30226566) Intraocular pressure ( 29617998 29235454) Ischemic stroke ( 29930801) LDL cholesterol ( 26160806) Lung cancer ( 28604730) Myocardial infarction ( 30226566) Pulse pressure ( 27841878)	Glucose homeostasis traits ( 25524916) Hemostatic factors and hematological phenotypes ( 22443383) Hippocampal sclerosis ( 25188341) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		12 interacting genes: ALPG CDT1 DYSF GBX2 GFRA3 KCNJ13 MMP2 NGFR PPT1 SEPTIN2 SUDS3 TRIT1	9 interacting genes: BRMS1 COL6A3 CSNK2A1 DYNLL1 GOLGA2 HDAC1 LDOC1 PTEN SRPK1
Entrez ID		1293	64426
HPRD ID		00371	12196
Ensembl ID		ENSG00000163359	ENSG00000111707
Uniprot IDs		B7ZW00 D9ZGF2 P12111 Q63HQ4 Q8N4Z1	Q9H7L9
PDB IDs		1KNT 1KTH 1KUN 2KNT 6SNK
Enriched GO Terms of Interacting Partners?
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