COL6A3 and TRIT1

		COL6A3	TRIT1
Description		collagen type VI alpha 3 chain	tRNA isopentenyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type VI Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Mitochondrion Mitochondrial Matrix
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Conferring Tensile Strength	Nucleic Acid Binding ATP Binding Zinc Ion Binding TRNA Dimethylallyltransferase Activity
	Biological Process	Cell Adhesion Muscle Organ Development Negative Regulation Of Endopeptidase Activity	TRNA Modification Mitochondrial TRNA Modification
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization	tRNA modification in the nucleus and cytosol tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Aging (time to event) ( 21782286) Chronic kidney disease ( 30226566) Coronary artery disease ( 29212778 30402224 33020668) Cortex volume ( 31530798) HDL cholesterol ( 26160806) Heel bone mineral density ( 30598549) Height ( 33713608) Hypertension ( 30226566) Intraocular pressure ( 29617998 29235454) Ischemic stroke ( 29930801) LDL cholesterol ( 26160806) Lung cancer ( 28604730) Myocardial infarction ( 30226566) Pulse pressure ( 27841878)	Refractive error ( 32231278)
Interacting Genes		12 interacting genes: ALPG CDT1 DYSF GBX2 GFRA3 KCNJ13 MMP2 NGFR PPT1 SEPTIN2 SUDS3 TRIT1	6 interacting genes: ANKS1A COL6A3 HGH1 OGT SHE SMYD3
Entrez ID		1293	54802
HPRD ID		00371	18226
Ensembl ID		ENSG00000163359	ENSG00000043514
Uniprot IDs		B7ZW00 D9ZGF2 P12111 Q63HQ4 Q8N4Z1	Q3T7C7 Q53F11 Q9H3H1
PDB IDs		1KNT 1KTH 1KUN 2KNT 6SNK
Enriched GO Terms of Interacting Partners?
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