ROPN1 and SYTL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ROPN1	SYTL4
Description		rhophilin associated tail protein 1	synaptotagmin like 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Motile Cilium	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Phospholipid Binding Small GTPase Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium	Plasma Membrane Repair Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair
Pathways		RHO GTPases Activate Rhotekin and Rhophilins	Platelet degranulation
Drugs			Insulin pork
Diseases
GWAS		Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)	Lean body mass ( 28552196) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		51 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM162A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3	27 interacting genes: CCDC85B CEP70 DVL3 FCHO1 FXR2 HMG20A INS KIFC3 LMO1 LZTS1 OSBPL3 PRKAR1B RAB27A RAB27B RAB3A RAB3D RAB8A ROPN1 SPANXN2 STX1A STXBP1 TBC1D1 TRIM37 TRIM41 ZBTB7B ZBTB9 ZRANB1
Entrez ID		54763	94121
HPRD ID		15269	06735
Ensembl ID		ENSG00000065371	ENSG00000102362
Uniprot IDs		A0A140VKB2 Q9HAT0	A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24
PDB IDs			2CSZ 3FDW 5X6T
Enriched GO Terms of Interacting Partners?
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