ROPN1 and POLR3C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ROPN1	POLR3C
Description		rhophilin associated tail protein 1	RNA polymerase III subunit C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Motile Cilium	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Single-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		RHO GTPases Activate Rhotekin and Rhophilins	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		51 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM162A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3	40 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD OGT PAX6 PICK1 PNMA5 POLR3G POLR3GL POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN
Entrez ID		54763	10623
HPRD ID		15269	17880
Ensembl ID		ENSG00000065371	ENSG00000186141
Uniprot IDs		A0A140VKB2 Q9HAT0	Q9BUI4
PDB IDs			2XUB 2XV4 5AFQ 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59
Enriched GO Terms of Interacting Partners?
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