POR and CYP2D6

  • Number of citations of the paper that reports this interaction (PubMedID 15680923)
  • 23
  • Data Source:
  • BioGRID (pull down, pull down)

POR

CYP2D6

Description cytochrome p450 oxidoreductase cytochrome P450 family 2 subfamily D member 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Intelligence ( 28530673)
  • Refractive error ( 32231278)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Schizophrenia ( 25056061 29483656)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes 21 interacting genes: CYB5A CYP17A1 CYP1A2 CYP2A6 CYP2C19 CYP2C9 CYP2D6 CYP2E1 CYP3A4 EHMT2 FANCC HMOX1 LINC01554 PSPHP1 RABEPK RPS4X SIN3B SLC39A2 STAT1 TGFBI XRCC6 3 interacting genes: CYB5A CYP2C9 POR
Entrez ID 5447 1565
HPRD ID 00485 00487
Ensembl ID ENSG00000100197
Uniprot IDs P16435 C1ID52 P10635 Q5Y7H2
PDB IDs 1B1C 3FJO 3QE2 3QFC 3QFR 3QFS 3QFT 5EMN 5FA6 2F9Q 3QM4 3TBG 3TDA 4WNT 4WNU 4WNV 4WNW 4XRY 4XRZ 5TFT 5TFU 6CSB 6CSD
Enriched GO Terms of Interacting Partners?
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