POR and CYP2C19

  • Number of citations of the paper that reports this interaction (PubMedID 9398194)
  • 41

POR

CYP2C19

Description cytochrome p450 oxidoreductase cytochrome P450 family 2 subfamily C member 19
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acenocoumarol maintenance dosage ( 19578179)
  • Clopidogrel active metabolite levels ( 28207573)
  • Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia ( 32555152)
  • Diastolic blood pressure ( 27841878 27618448)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Mean arterial pressure ( 27618448)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Pulse pressure ( 27841878)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure ( 27841878 30578418)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Warfarin maintenance dose ( 23755828)
Interacting Genes 21 interacting genes: CYB5A CYP17A1 CYP1A2 CYP2A6 CYP2C19 CYP2C9 CYP2D6 CYP2E1 CYP3A4 EHMT2 FANCC HMOX1 LINC01554 PSPHP1 RABEPK RPS4X SIN3B SLC39A2 STAT1 TGFBI XRCC6 1 interacting genes: POR
Entrez ID 5447 1557
HPRD ID 00485 00486
Ensembl ID ENSG00000165841
Uniprot IDs P16435 P33261
PDB IDs 1B1C 3FJO 3QE2 3QFC 3QFR 3QFS 3QFT 5EMN 5FA6 4GQS
Enriched GO Terms of Interacting Partners?
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