MIOS and SESN1

Number of citations of the paper that reports this interaction (PubMedID 25263562)
166

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MIOS	SESN1
Description		meiosis regulator for oocyte development	sestrin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Lysosomal Membrane Cytosol Cell Junction GATOR2 Complex	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Oxidoreductase Activity, Acting On Peroxide As Acceptor Peroxiredoxin Activity Leucine Binding
	Biological Process	Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein-containing Complex Localization	Positive Regulation Of Macroautophagy Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Cellular Response To Leucine Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Regulation Of Response To Reactive Oxygen Species Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation
Pathways		Amino acids regulate mTORC1	Amino acids regulate mTORC1
Drugs
Diseases
GWAS			Asthma ( 32296059) Birth weight ( 31043758) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		3 interacting genes: NTAQ1 SESN1 SESN3	3 interacting genes: MIOS PRDX1 WDR24
Entrez ID		54468	27244
HPRD ID		07898	07310
Ensembl ID		ENSG00000164654	ENSG00000080546
Uniprot IDs		A0A024RA24 Q9NXC5	Q9Y6P5
PDB IDs
Enriched GO Terms of Interacting Partners?
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