MIOS and SESN3

Number of citations of the paper that reports this interaction (PubMedID 25263562)
166

Data Source:
BioGRID (pull down)

		MIOS	SESN3
Description		meiosis regulator for oocyte development	sestrin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Lysosomal Membrane Cytosol Cell Junction GATOR2 Complex	Nucleus Cytoplasm TORC2 Complex
	Molecular Function	Protein Binding	Protein Binding Oxidoreductase Activity, Acting On Peroxide As Acceptor Leucine Binding
	Biological Process	Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein-containing Complex Localization	Positive Regulation Of Macroautophagy Response To Insulin Cellular Response To Amino Acid Starvation TORC2 Signaling Cellular Response To Glucose Starvation Glucose Homeostasis Regulation Of Insulin Receptor Signaling Pathway Regulation Of Protein Kinase B Signaling Cellular Response To Leucine Regulation Of Response To Reactive Oxygen Species Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation
Pathways		Amino acids regulate mTORC1	TP53 Regulates Metabolic Genes
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Aspartate aminotransferase levels ( 33547301) Chronotype ( 30696823) Common carotid intima-media thickness ( 29206233) Common carotid intima-media thickness in HIV infection ( 29206233) Diastolic blood pressure ( 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		3 interacting genes: NTAQ1 SESN1 SESN3	4 interacting genes: MIOS NPRL3 WDR24 WDR59
Entrez ID		54468	143686
HPRD ID		07898	09682
Ensembl ID		ENSG00000164654	ENSG00000149212
Uniprot IDs		A0A024RA24 Q9NXC5	P58005
PDB IDs
Enriched GO Terms of Interacting Partners?
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