DUOX1 and TXNDC11

Number of citations of the paper that reports this interaction (PubMedID 15561711)
22

Data Source:
HPRD (in vivo, two hybrid)

		DUOX1	TXNDC11
Description		dual oxidase 1	thioredoxin domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell Surface Apical Plasma Membrane Cell Leading Edge NADPH Oxidase Complex	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Peroxidase Activity Calcium Ion Binding Protein Binding NAD(P)H Oxidase H2O2-forming Activity Superoxide-generating NAD(P)H Oxidase Activity Heme Binding NADP Binding NADH Oxidase H202-forming Activity NADPH Oxidase H202-forming Activity	Protein Binding
	Biological Process	Thyroid Hormone Generation Defense Response Response To Oxidative Stress Cytokine-mediated Signaling Pathway Cuticle Development Hormone Biosynthetic Process Superoxide Anion Generation Hydrogen Peroxide Catabolic Process Hydrogen Peroxide Biosynthetic Process Response To CAMP Positive Regulation Of Wound Healing Cellular Oxidant Detoxification Positive Regulation Of Cell Motility
Pathways		Thyroxine biosynthesis
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		2 interacting genes: TPO TXNDC11	21 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417
Entrez ID		53905	51061
HPRD ID		08421	07125
Ensembl ID		ENSG00000137857	ENSG00000153066
Uniprot IDs		Q9NRD9	Q6PKC3
PDB IDs		7D3E 7D3F
Enriched GO Terms of Interacting Partners?
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