TXNDC11 and ACAA1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TXNDC11	ACAA1
Description		thioredoxin domain containing 11	acetyl-CoA acyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Extracellular Region Peroxisome Peroxisomal Matrix Cytosol Membrane Specific Granule Lumen
	Molecular Function	Protein Binding	Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Acetate CoA-transferase Activity Palmitoyl-CoA Oxidase Activity Acetyl-CoA C-myristoyltransferase Activity
	Biological Process		Very Long-chain Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Metabolic Process Phenylacetate Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process
Pathways			alpha-linolenic acid (ALA) metabolism Beta-oxidation of very long chain fatty acids Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs			Trimetazidine
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Weight ( 28552196)	Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		21 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417	4 interacting genes: FEM1A HAT1 TFCP2 TXNDC11
Entrez ID		51061	30
HPRD ID		07125	06815
Ensembl ID		ENSG00000153066	ENSG00000060971
Uniprot IDs		Q6PKC3	A0A024R2M6 A0A140VJX0 P09110
PDB IDs			2IIK
Enriched GO Terms of Interacting Partners?
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