TXNDC11 and DUOX1

Number of citations of the paper that reports this interaction (PubMedID 15561711)
22

Data Source:
HPRD (in vivo, two hybrid)

		TXNDC11	DUOX1
Description		thioredoxin domain containing 11	dual oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Plasma Membrane Cell Surface Apical Plasma Membrane Cell Leading Edge NADPH Oxidase Complex
	Molecular Function	Protein Binding	Peroxidase Activity Calcium Ion Binding Protein Binding NAD(P)H Oxidase H2O2-forming Activity Superoxide-generating NAD(P)H Oxidase Activity Heme Binding NADP Binding NADH Oxidase H202-forming Activity NADPH Oxidase H202-forming Activity
	Biological Process		Thyroid Hormone Generation Defense Response Response To Oxidative Stress Cytokine-mediated Signaling Pathway Cuticle Development Hormone Biosynthetic Process Superoxide Anion Generation Hydrogen Peroxide Catabolic Process Hydrogen Peroxide Biosynthetic Process Response To CAMP Positive Regulation Of Wound Healing Cellular Oxidant Detoxification Positive Regulation Of Cell Motility
Pathways			Thyroxine biosynthesis
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		21 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417	2 interacting genes: TPO TXNDC11
Entrez ID		51061	53905
HPRD ID		07125	08421
Ensembl ID		ENSG00000153066	ENSG00000137857
Uniprot IDs		Q6PKC3	Q9NRD9
PDB IDs			7D3E 7D3F
Enriched GO Terms of Interacting Partners?
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