SERPINA4 and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		SERPINA4	TNNT1
Description		serpin family A member 4	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Dense Granule Lumen Extracellular Exosome	Cytosol Troponin Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity	Protein Binding Tropomyosin Binding Troponin T Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction
Pathways		Platelet degranulation	Striated Muscle Contraction
Drugs		Zinc Copper Zinc acetate
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Vaspin levels ( 22907691)	Height ( 31562340)
Interacting Genes		14 interacting genes: CTSD GADD45G ILK KLK1 KLK2 MAP4K2 MAPK6 NR4A1 RASA1 TAB1 TNFRSF14 TNNT1 TRIP11 YAE1	69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		5267	7138
HPRD ID		01004	01841
Ensembl ID		ENSG00000100665	ENSG00000105048
Uniprot IDs		A0A024R6I9 P29622	P13805
PDB IDs		6F02
Enriched GO Terms of Interacting Partners?
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