TNNT1 and ARMC8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TNNT1	ARMC8
Description		troponin T1, slow skeletal type	armadillo repeat containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Intracellular Membrane-bounded Organelle Tertiary Granule Lumen
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Striated Muscle Contraction	Neutrophil degranulation
Drugs
Diseases
GWAS		Height ( 31562340)	Body shape index ( 34021172) Mean spheric corpuscular volume ( 32888494) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	11 interacting genes: CIB3 CTNNA1 GID8 MAEA PKP1 PKP2 PKP4 STX6 TCF12 TNNT1 ZMYND12
Entrez ID		7138	25852
HPRD ID		01841	09992
Ensembl ID		ENSG00000105048	ENSG00000114098
Uniprot IDs		P13805	B7Z637 Q8IUR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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