PGK1 and RHOU

Number of citations of the paper that reports this interaction (PubMedID 26598620)
28

Data Source:
BioGRID (pull down)

		PGK1	RHOU
Description		phosphoglycerate kinase 1	ras homolog family member U
Image
GO Annotations	Cellular Component	Extracellular Space Cytosol Membrane Membrane Raft Extracellular Exosome	Golgi Membrane Podosome Cytosol Plasma Membrane Focal Adhesion Cell Projection
	Molecular Function	Phosphoglycerate Kinase Activity Protein Binding ATP Binding ADP Binding Protein-disulfide Reductase (NAD(P)) Activity	GTPase Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding Metal Ion Binding
	Biological Process	Gluconeogenesis Glycolytic Process Phosphorylation Negative Regulation Of Angiogenesis Epithelial Cell Differentiation Plasminogen Activation Cellular Response To Hypoxia	Endocytosis Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Cell Projection Assembly Cdc42 Protein Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Glycolysis Gluconeogenesis Manipulation of host energy metabolism	Interleukin-4 and Interleukin-13 signaling RHOU GTPase cycle RHOU GTPase cycle
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate 3-phospho-D-glyceric acid Copper Artenimol
Diseases
GWAS		Mean platelet volume ( 32888494)	Aging ( 22773346) Basal cell carcinoma ( 33549134 24403052 25855136 27539887 18849993) Chronic lymphocytic leukemia ( 28165464) Dental caries ( 23259602) Endometriosis ( 20844546) Leukoderma in response to rhododendrol ( 32558222) Mercury levels ( 26025379) Non-melanoma skin cancer ( 29739929) Response to antidepressants in depression ( 27622933) Type 2 diabetes ( 23300278)
Interacting Genes		18 interacting genes: AR BECN1 CDC7 CSNK2A1 DISC1 GAPDH HIF1A HSPH1 LINC01554 NAA10 OGT PCNA RHOU SUMO2 SUMO4 TUBA1A UBE3A YWHAQ	128 interacting genes: ACAD8 ADM2 ALG13 ANGPT4 ANXA4 ANXA6 AP1S1 ARHGEF25 ARNTL AS3MT ATP5MG ATP6AP1 BDNF BNIPL BRF1 BRINP3 C14orf119 CDKL4 CFAP100 CHRNA4 CLEC7A CPNE3 CTCF CUL5 DACT2 DMRT2 DNM2 DOK4 DSCR8 EIF4B ELP5 EMC2 ERF ERO1A ESYT1 FAM110B FCHO2 FKBP15 GALNTL5 GLI3 GPRIN2 GRB2 H2BC14 HCAR1 HINT3 HSD17B13 ID2 IFFO1 IL17F INSM2 JAM3 KAAG1 KIAA1191 KLRC3 LANCL2 LARS2 LAYN LMO7 LYL1 MARCKS ME3 MOS MRAS MRPL15 NCK1 NCR1 NPM3 NR1H2 NRBF2 NXPH4 OXCT2 P4HTM PAK1 PAK4 PCDHGA4 PDLIM3 PGK1 PIP5K1A PLCG1 PLEK PLOD3 POT1 PRB1 PRPF18 PSMA4 PXN QTRT1 RAB40A RAD51D RALBP1 RASSF1 RBIS RPL23AP5 RPS15A RPS17P16 S100A4 SEC14L4 SEMA3G SEPTIN6 SIVA1 SKIV2L SLC26A1 SNU13 SOX4 SSC4D STX16 SYK TCN2 TEKT2 TMEM106A TMEM169 TMEM255B TRIM59 USP37 UTP3 VWA5A WNT6 XPA ZFAND2B ZFP64 ZKSCAN7 ZNF117 ZNF177 ZNF20 ZNF569 ZNF625 ZNF747 ZNF84
Entrez ID		5230	58480
HPRD ID		02412	06965
Ensembl ID		ENSG00000102144	ENSG00000116574
Uniprot IDs		P00558 V9HWF4	A0A024R3Q7 Q7L0Q8
PDB IDs		2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE 2ZGV 3C39 3C3A 3C3B 3C3C 3ZOZ 4AXX 4O33 5M1R 5M3U 5M6Z 5MXM 5NP8 5O7D	2Q3H
Enriched GO Terms of Interacting Partners?
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