PENK and ADD3

		PENK	ADD3
Description		proenkephalin	adducin 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Plasma Membrane Dendrite Symmetric Synapse Chromaffin Granule Lumen Synaptic Vesicle Lumen Neuronal Cell Body Perikaryon Axon Terminus Cell Body Fiber Neuronal Dense Core Vesicle Lumen	Condensed Nuclear Chromosome Cytosol Cytoskeleton Plasma Membrane Brush Border Cell-cell Junction Cell Cortex Postsynaptic Density Membrane
	Molecular Function	Opioid Peptide Activity Neuropeptide Hormone Activity Opioid Receptor Binding	Structural Constituent Of Cytoskeleton Calmodulin Binding Actin Filament Binding
	Biological Process	Osteoblast Differentiation Behavioral Fear Response Response To Hypoxia Startle Response Aggressive Behavior Signal Transduction Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Sensory Perception Response To Radiation Response To Toxic Substance Glial Cell Proliferation Sensory Perception Of Pain Response To Estradiol Response To Lipopolysaccharide Cellular Response To Oxidative Stress Response To Nicotine Locomotory Exploration Behavior Response To Morphine Response To Ethanol Response To Calcium Ion General Adaptation Syndrome, Behavioral Process Cellular Response To Vitamin D Cellular Response To CAMP Cellular Response To Transforming Growth Factor Beta Stimulus Response To Epinephrine Cellular Response To Virus Synaptic Signaling Via Neuropeptide Positive Regulation Of Behavioral Fear Response	Cytoskeleton Organization Barbed-end Actin Filament Capping
Pathways		Peptide ligand-binding receptors Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (i) signalling events Post-translational protein phosphorylation	Miscellaneous transport and binding events RHOD GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Height ( 18391951) Problematic alcohol use ( 32451486) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Suicide in bipolar disorder ( 25917933)	Biliary atresia ( 20460270) Bipolar disorder ( 33263727 31043756 28072414) Cutaneous melanoma or hair colour ( 32341527) Metabolite levels ( 23823483) Neutrophil count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010)
Interacting Genes		2 interacting genes: ADD3 HSP90AB1	13 interacting genes: AGTR1 ATXN1 CWF19L1 GNG13 HSPB1 OPRM1 PENK PRKCA RPL4 TRIM8 TUBGCP4 UBE2I ZNF76
Entrez ID		5179	120
HPRD ID		08837	03339
Ensembl ID		ENSG00000181195	ENSG00000148700
Uniprot IDs		A0A024R7V4 P01210	Q53FL4 Q59EK1 Q5VU08 Q9UEY8
PDB IDs		1PLW 1PLX 2LWC 5E33 5E3A
Enriched GO Terms of Interacting Partners?
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