ADD3 and RPL4

		ADD3	RPL4
Description		adducin 3	ribosomal protein L4
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Cytosol Cytoskeleton Plasma Membrane Brush Border Cell-cell Junction Cell Cortex Postsynaptic Density Membrane	Nucleus Nucleolus Cytoplasm Rough Endoplasmic Reticulum Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Calmodulin Binding Actin Filament Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Cytoskeleton Organization Barbed-end Actin Filament Capping	Cytoplasmic Translation Translation
Pathways		Miscellaneous transport and binding events RHOD GTPase cycle RHOF GTPase cycle	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS		Biliary atresia ( 20460270) Bipolar disorder ( 33263727 31043756 28072414) Cutaneous melanoma or hair colour ( 32341527) Metabolite levels ( 23823483) Neutrophil count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010)
Interacting Genes		13 interacting genes: AGTR1 ATXN1 CWF19L1 GNG13 HSPB1 OPRM1 PENK PRKCA RPL4 TRIM8 TUBGCP4 UBE2I ZNF76	19 interacting genes: ADD3 APBB1 APOE DUX4 DUX4L9 IL32 MAP3K14 MDM2 MYB NDRG1 OGT PBX2 PIN1 PRPF40A SORBS1 SUMO2 TLE3 TNPO2 TSC2
Entrez ID		120	6124
HPRD ID		03339	01607
Ensembl ID		ENSG00000148700	ENSG00000174444
Uniprot IDs		Q53FL4 Q59EK1 Q5VU08 Q9UEY8	P36578
PDB IDs			4UG0 4V6X 5A8L 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP
Enriched GO Terms of Interacting Partners?
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