KDM3B and ZNF512B

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
BioGRID (two hybrid)

		KDM3B	ZNF512B
Description		lysine demethylase 3B	zinc finger protein 512B
Image
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm	Nucleoplasm
	Molecular Function	Transcription Coregulator Activity Antioxidant Activity Chromatin DNA Binding Histone H3-methyl-lysine-9 Demethylase Activity Metal Ion Binding Dioxygenase Activity	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation Response To Cisplatin Cellular Oxidant Detoxification
Pathways		HDMs demethylate histones	RHOV GTPase cycle
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) HIV-1 susceptibility ( 25786224) Menarche (age at onset) ( 21102462 25231870) Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689) Schizophrenia ( 25056061)	Birth weight ( 31043758) Mean platelet volume ( 32888494) Offspring birth weight ( 31043758) Prostate cancer ( 23535732) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		14 interacting genes: CDKL3 CREBBP FAM13B FAM53C H3-4 PCDH12 PCDHGB7 PCDHGC4 PCDHGC5 REEP2 RNF41 SPAG8 UBC ZNF512B	71 interacting genes: AJUBA ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BANP BRD1 BTBD2 C11orf68 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 GOLGA2 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MDFI MEOX2 MTUS2 MYH10 NACC1 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RABEP1 RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2 ZNF143 ZYX
Entrez ID		51780	57473
HPRD ID		11055	13840
Ensembl ID		ENSG00000120733	ENSG00000196700
Uniprot IDs		Q7LBC6	Q96KM6
PDB IDs		4C8D 5R7X 5RAA 5RAB 5RAC 5RAD 5RAE 5RAF 5RAG 5RAH 5RAI 5RAJ 5RAK 5RAL 5RAM 5RAN 5RAO 5RAP 5RAQ 5RAR 5RAS 5RAU 5RAV 5RAW 5RAX 5RAY 5RAZ 5RB0 5RB1 5RB2 5RB3 5RB4 5RB5 5RB6 5RB7 6RBJ	2GQJ
Enriched GO Terms of Interacting Partners?
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