KDM3B and REEP2

		KDM3B	REEP2
Description		lysine demethylase 3B	receptor accessory protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Integral Component Of Plasma Membrane Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Transcription Coregulator Activity Antioxidant Activity Chromatin DNA Binding Histone H3-methyl-lysine-9 Demethylase Activity Metal Ion Binding Dioxygenase Activity	Protein Binding Microtubule Binding Taste Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation Response To Cisplatin Cellular Oxidant Detoxification	Regulation Of Intracellular Transport Protein Transport Into Membrane Raft Sensory Perception Of Bitter Taste Sensory Perception Of Sweet Taste Endoplasmic Reticulum Tubular Network Organization
Pathways		HDMs demethylate histones	Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) HIV-1 susceptibility ( 25786224) Menarche (age at onset) ( 21102462 25231870) Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689) Schizophrenia ( 25056061)	Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061)
Interacting Genes		14 interacting genes: CDKL3 CREBBP FAM13B FAM53C H3-4 PCDH12 PCDHGB7 PCDHGC4 PCDHGC5 REEP2 RNF41 SPAG8 UBC ZNF512B	25 interacting genes: BNIP3 C2CD2L CMTM5 CYP4F2 CYP4F22 ITGAM KDM3B MS4A1 MUL1 NAT8 ORMDL3 RABAC1 SCD SFT2D2 SLC25A46 TMBIM6 TMEM120B TMEM208 TMEM239 TMEM31 TMEM42 TMEM60 TMX2 TTPA YIF1A
Entrez ID		51780	51308
HPRD ID		11055	16655
Ensembl ID		ENSG00000120733	ENSG00000132563
Uniprot IDs		Q7LBC6	A8K3D2 Q9BRK0
PDB IDs		4C8D 5R7X 5RAA 5RAB 5RAC 5RAD 5RAE 5RAF 5RAG 5RAH 5RAI 5RAJ 5RAK 5RAL 5RAM 5RAN 5RAO 5RAP 5RAQ 5RAR 5RAS 5RAU 5RAV 5RAW 5RAX 5RAY 5RAZ 5RB0 5RB1 5RB2 5RB3 5RB4 5RB5 5RB6 5RB7 6RBJ
Enriched GO Terms of Interacting Partners?
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