KDM3B and FAM13B

		KDM3B	FAM13B
Description		lysine demethylase 3B	family with sequence similarity 13 member B
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm	Cytosol
	Molecular Function	Transcription Coregulator Activity Antioxidant Activity Chromatin DNA Binding Histone H3-methyl-lysine-9 Demethylase Activity Metal Ion Binding Dioxygenase Activity	GTPase Activator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation Response To Cisplatin Cellular Oxidant Detoxification	Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		HDMs demethylate histones	CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) HIV-1 susceptibility ( 25786224) Menarche (age at onset) ( 21102462 25231870) Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689) Schizophrenia ( 25056061)	Atrial fibrillation ( 28416818 30061737 29892015) Autism spectrum disorder or schizophrenia ( 28540026) Plateletcrit ( 32888494)
Interacting Genes		14 interacting genes: CDKL3 CREBBP FAM13B FAM53C H3-4 PCDH12 PCDHGB7 PCDHGC4 PCDHGC5 REEP2 RNF41 SPAG8 UBC ZNF512B	9 interacting genes: AGTR1 CDC42 KDM3B LINC00839 RAC1 SAMHD1 YWHAE YWHAG YWHAZ
Entrez ID		51780	51306
HPRD ID		11055	06464
Ensembl ID		ENSG00000120733	ENSG00000031003
Uniprot IDs		Q7LBC6	A0A2X0SG06 Q9NYF5
PDB IDs		4C8D 5R7X 5RAA 5RAB 5RAC 5RAD 5RAE 5RAF 5RAG 5RAH 5RAI 5RAJ 5RAK 5RAL 5RAM 5RAN 5RAO 5RAP 5RAQ 5RAR 5RAS 5RAU 5RAV 5RAW 5RAX 5RAY 5RAZ 5RB0 5RB1 5RB2 5RB3 5RB4 5RB5 5RB6 5RB7 6RBJ
Enriched GO Terms of Interacting Partners?
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