SFMBT1 and SPANXN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SFMBT1	SPANXN2
Description		Scm like with four mbt domains 1	SPANX family member N2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding	Protein Binding
	Biological Process	Chromatin Organization Spermatogenesis Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Organ Development
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Body shape index ( 34021172) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 29124443) General cognitive ability ( 29844566) Gout ( 33832965 31578528) Haemorrhoidal disease ( 33888516) Hand grip strength ( 29691431) Height ( 28552196 31562340 31217584) Hip circumference ( 28552196) Hyperuricemia ( 29124443) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Schizophrenia ( 28991256 23974872) Serum uric acid levels ( 30993211 29124443 29403010) Type 2 diabetes (age of onset) ( 28060188) Urate levels ( 31985003 31578528 23263486) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: ACP1 CLNK FAM214B HOXB9 PHC1 PHC2 PSMA1 SCMH1 SPANXN2 SRPK1 ZCCHC10	51 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BHLHB9 BIVM CAVIN1 CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84
Entrez ID		51460	494119
HPRD ID		09539	18091
Ensembl ID		ENSG00000163935	ENSG00000268988
Uniprot IDs		A0A024R338 Q9UHJ3	Q5MJ10
PDB IDs
Enriched GO Terms of Interacting Partners?
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