SFMBT1 and SCMH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SFMBT1	SCMH1
Description		Scm like with four mbt domains 1	Scm polycomb group protein homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Chromocenter
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Chromatin Organization Spermatogenesis Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Organ Development	Chromatin Remodeling Spermatogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs			Mercaptoethanol
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Body shape index ( 34021172) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 29124443) General cognitive ability ( 29844566) Gout ( 33832965 31578528) Haemorrhoidal disease ( 33888516) Hand grip strength ( 29691431) Height ( 28552196 31562340 31217584) Hip circumference ( 28552196) Hyperuricemia ( 29124443) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Multiple sclerosis ( 31604244) Schizophrenia ( 28991256 23974872) Serum uric acid levels ( 30993211 29124443 29403010) Type 2 diabetes (age of onset) ( 28060188) Urate levels ( 31985003 31578528 23263486) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737 29892015) General risk tolerance (MTAG) ( 30643258) Height ( 20881960 25282103 23563607 18391952) Hip circumference adjusted for BMI ( 34021172) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928)
Interacting Genes		11 interacting genes: ACP1 CLNK FAM214B HOXB9 PHC1 PHC2 PSMA1 SCMH1 SPANXN2 SRPK1 ZCCHC10	22 interacting genes: EWSR1 FXR1 FXR2 GMNN HK1 HPCAL4 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M SFMBT1 SFMBT2 TMEM11 TOB1 TSC1 UBQLN1 UBQLN4
Entrez ID		51460	22955
HPRD ID		09539	11540
Ensembl ID		ENSG00000163935	ENSG00000010803
Uniprot IDs		A0A024R338 Q9UHJ3	B3KMZ7 Q96GD3
PDB IDs			2P0K
Enriched GO Terms of Interacting Partners?
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