HPCAL4 and CEACAM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HPCAL4	CEACAM6
Description		hippocalcin like 4	CEA cell adhesion molecule 6
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Domain Specific Binding	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Signal Transduction Central Nervous System Development	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways			Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699)	Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		17 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 CNTROB DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A	32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76
Entrez ID		51440	4680
HPRD ID		17113	01233
Ensembl ID		ENSG00000116983	ENSG00000086548
Uniprot IDs		B4DGW9 Q9UM19	P40199
PDB IDs			4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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