CEACAM6 and CEACAM8

Number of citations of the paper that reports this interaction (PubMedID 2022629)
24

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CEACAM6	CEACAM8
Description		CEA cell adhesion molecule 6	CEA cell adhesion molecule 8
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane	Extracellular Space Plasma Membrane Cell Surface Anchored Component Of Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Protein Binding Protein Heterodimerization Activity
	Biological Process	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis	Immune Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation	Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76	2 interacting genes: CEACAM1 CEACAM6
Entrez ID		4680	1088
HPRD ID		01233	07630
Ensembl ID		ENSG00000086548	ENSG00000124469
Uniprot IDs		P40199	B4DLI3 P31997 Q0Z7S6
PDB IDs		4WHC 4WTZ 4Y8A 4YIQ	2DKS 4WTZ 4Y88 4YIQ
Enriched GO Terms of Interacting Partners?
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