PPME1 and CAMK1

Number of citations of the paper that reports this interaction (PubMedID 24841198)
7

Data Source:
BioGRID (enzymatic study)

		PPME1	CAMK1
Description		protein phosphatase methylesterase 1	calcium/calmodulin dependent protein kinase I
Image
GO Annotations	Cellular Component	Nucleoplasm	Intracellular Anatomical Structure Nucleus Cytosol Postsynaptic Density Glutamatergic Synapse
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Protein Kinase Binding Protein Phosphatase Binding Cadherin Binding Protein Phosphatase 2A Binding Protein C-terminal Methylesterase Activity Protein Methylesterase Activity	Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Demethylation Negative Regulation Of Catalytic Activity	Protein Phosphorylation Nucleocytoplasmic Transport Cell Cycle Signal Transduction Nervous System Development Positive Regulation Of Neuron Projection Development Peptidyl-serine Phosphorylation Cell Differentiation Negative Regulation Of Protein Binding Regulation Of Protein Localization Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Export From Nucleus Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Dendritic Spine Development Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Acetylation Regulation Of Histone H3-K9 Acetylation
Pathways		Cyclin A/B1/B2 associated events during G2/M transition	Negative regulation of NMDA receptor-mediated neuronal transmission Activation of RAC1 downstream of NMDARs Activation of RAC1 downstream of NMDARs
Drugs			Fostamatinib
Diseases
GWAS
Interacting Genes		1 interacting genes: CAMK1	22 interacting genes: APP ATF1 ATXN1 CALM1 CAMKK1 CAMKK2 CCND1 CDK4 CDKN1B EIF4G3 FBXO7 GAPDH GCM1 HDAC5 HSPB1 IL16 MARK2 NOS1 PIK3R3 PPME1 PPP2CA SYN1
Entrez ID		51400	8536
HPRD ID		17864	05412
Ensembl ID		ENSG00000214517	ENSG00000134072
Uniprot IDs		A0A140VK39 Q9Y570	B0YIY3 Q14012
PDB IDs		3C5V 3C5W	4FG7 4FG8 4FG9 4FGB
Enriched GO Terms of Interacting Partners?
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