WAC and DYDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		WAC	DYDC1
Description		WW domain containing adaptor with coiled-coil	DPY30 domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Chromosome, Telomeric Region MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Regulation Of Autophagy Positive Regulation Of Macroautophagy Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination Positive Regulation Of TORC1 Signaling	Histone H3-K4 Methylation
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)	Estimated glomerular filtration rate ( 31451708)
Interacting Genes		25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	34 interacting genes: ARNT2 CCHCR1 CCNC CEP57L1 DPY30 ENKD1 GHITM HDAC4 HGS KRT75 LMO2 LNX1 MID2 MOS NME5 PDZD4 PIK3R2 PKN1 POU6F2 PPP2R5D PSMA1 TCHP TEAD4 TFPT TLE5 TSGA10IP TXLNB TXNDC9 USHBP1 USP2 VPS37C VPS9D1 WAC ZGPAT
Entrez ID		51322	143241
HPRD ID		18291	14062
Ensembl ID		ENSG00000095787	ENSG00000170788
Uniprot IDs		Q9BTA9	Q8WWB3
PDB IDs
Enriched GO Terms of Interacting Partners?
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