WAC and MOBP

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		WAC	MOBP
Description		WW domain containing adaptor with coiled-coil	myelin associated oligodendrocyte basic protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Cortical Actin Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	Actin Binding Protein Binding Myosin Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Regulation Of Autophagy Positive Regulation Of Macroautophagy Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination Positive Regulation Of TORC1 Signaling	Nervous System Development
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	Transcriptional Regulation by MECP2
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)	Alzheimer's disease (cognitive decline) ( 23535033) Amyotrophic lateral sclerosis ( 27455348) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Attention deficit hyperactivity disorder ( 18839057) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive performance ( 19734545) Cortical surface area (MOSTest) ( 32665545) Corticobasal degeneration ( 26077951) Dentate gyrus volume x schizophrenia interaction ( 31155012) Progressive supranuclear palsy ( 30089514 21685912) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	21 interacting genes: APP BOLA2 BOLA2B KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 MEOX2 SDCBP TRIM41 WAC ZNF23
Entrez ID		51322	4336
HPRD ID		18291	02973
Ensembl ID		ENSG00000095787	ENSG00000168314
Uniprot IDs		Q9BTA9	A0A0S2Z3W1 Q13875
PDB IDs
Enriched GO Terms of Interacting Partners?
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