DYDC1 and WAC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		DYDC1	WAC
Description		DPY30 domain containing 1	WW domain containing adaptor with coiled-coil
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region MLL3/4 Complex Set1C/COMPASS Complex	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process	Histone H3-K4 Methylation	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Regulation Of Autophagy Positive Regulation Of Macroautophagy Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination Positive Regulation Of TORC1 Signaling
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708)	Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)
Interacting Genes		34 interacting genes: ARNT2 CCHCR1 CCNC CEP57L1 DPY30 ENKD1 GHITM HDAC4 HGS KRT75 LMO2 LNX1 MID2 MOS NME5 PDZD4 PIK3R2 PKN1 POU6F2 PPP2R5D PSMA1 TCHP TEAD4 TFPT TLE5 TSGA10IP TXLNB TXNDC9 USHBP1 USP2 VPS37C VPS9D1 WAC ZGPAT	25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17
Entrez ID		143241	51322
HPRD ID		14062	18291
Ensembl ID		ENSG00000170788	ENSG00000095787
Uniprot IDs		Q8WWB3	Q9BTA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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