PCBD1 and ZNF202

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PCBD1	ZNF202
Description		pterin-4 alpha-carbinolamine dehydratase 1	zinc finger protein 202
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Chromosome Nucleolus Nuclear Body
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	L-phenylalanine Metabolic Process Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process
Pathways		Phenylalanine metabolism	Generic Transcription Pathway
Drugs		L-erythro-7,8-dihydrobiopterin
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)	Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103) Response to citalopram or escitalopram in depression ( 27622933)
Interacting Genes		54 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KANK2 KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 PICK1 POLR3A PSMA1 RBL2 RPS24 SAP30 SCMH1 SDCBP SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714	25 interacting genes: CARD10 CEP70 EAF1 KRT40 KRTAP10-3 LMO4 LOX MAD2L1BP MCC MEOX2 MTIF3 MZF1 NAA10 NAA11 PCBD1 SCAND1 SCNM1 SEPHS1 SNX2 SSX2IP ZNF250 ZNF438 ZNF473 ZNF835 ZNF837
Entrez ID		5092	7753
HPRD ID		00523	04577
Ensembl ID		ENSG00000166228	ENSG00000166261
Uniprot IDs		P61457	A0A024R3M3 B3KN61 O95125
PDB IDs
Enriched GO Terms of Interacting Partners?
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