PCBD1 and ZNF714

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PCBD1	ZNF714
Description		pterin-4 alpha-carbinolamine dehydratase 1	zinc finger protein 714
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Nucleus
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	L-phenylalanine Metabolic Process Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II
Pathways		Phenylalanine metabolism	Generic Transcription Pathway
Drugs		L-erythro-7,8-dihydrobiopterin
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		54 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KANK2 KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 PICK1 POLR3A PSMA1 RBL2 RPS24 SAP30 SCMH1 SDCBP SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714	2 interacting genes: LZTR1 PCBD1
Entrez ID		5092	148206
HPRD ID		00523	18733
Ensembl ID		ENSG00000166228	ENSG00000160352
Uniprot IDs		P61457	A0A087WU35 Q96N38
PDB IDs
Enriched GO Terms of Interacting Partners?
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