PCBD1 and TFF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PCBD1	TFF3
Description		pterin-4 alpha-carbinolamine dehydratase 1	trefoil factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Secretory Granule
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	L-phenylalanine Metabolic Process Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated	Regulation Of Glucose Metabolic Process Maintenance Of Gastrointestinal Epithelium
Pathways		Phenylalanine metabolism	Estrogen-dependent gene expression
Drugs		L-erythro-7,8-dihydrobiopterin
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)	Spatial memory ( 31596458)
Interacting Genes		54 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KANK2 KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 PICK1 POLR3A PSMA1 RBL2 RPS24 SAP30 SCMH1 SDCBP SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714	6 interacting genes: PCBD1 SGTA SH3BGR TRAPPC10 UBQLN2 ZSCAN9
Entrez ID		5092	7033
HPRD ID		00523	02797
Ensembl ID		ENSG00000166228	ENSG00000160180
Uniprot IDs		P61457	Q07654
PDB IDs			1E9T 1PE3 6V1C
Enriched GO Terms of Interacting Partners?
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