CYHR1 and KPNA4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CYHR1	KPNA4
Description		cysteine and histidine rich 1	karyopherin subunit alpha 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytosol Nuclear Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process		NLS-bearing Protein Import Into Nucleus
Pathways			ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149 27798627) Blood metabolite levels ( 26401656) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) General cognitive ability ( 29844566)	Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Attention deficit hyperactivity disorder ( 32279069) Bipolar disorder ( 31043756) Malaria ( 31844061) Myeloproliferative neoplasms ( 33057200) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smooth-surface caries ( 24556642) Total cholesterol levels ( 30275531)
Interacting Genes		13 interacting genes: ALDH3A1 FXR1 HOXA1 KPNA3 KPNA4 KRTAP1-1 KRTAP1-3 LGALS3 MAPK9 NBPF19 NOTCH2NLA PVR SDCBP	27 interacting genes: APP CDKN1B CSE1L CSNK2A1 CUL4B CYHR1 EXO1 FAM50B GTF2IRD1 HIF1A HNRNPC HSD3B7 KAT5 KPNB1 MAT2B MTA1 NCBP3 NFE2L2 NTRK3 NUP50 OGT PLAA RAC1 RCC1 RECQL TGM2 WT1
Entrez ID		50626	3840
HPRD ID		13107	04275
Ensembl ID		ENSG00000187954	ENSG00000186432
Uniprot IDs		E9PJD7 Q6ZMK1	O00629
PDB IDs			4UAE 5TBK 5XZX 6BVV 6BVZ 6BW9 6BWA 6BWB 6WX8 7JJL
Enriched GO Terms of Interacting Partners?
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