KPNA4 and CYHR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		KPNA4	CYHR1
Description		karyopherin subunit alpha 4	cysteine and histidine rich 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Membrane	Nucleoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Protein Binding Zinc Ion Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Attention deficit hyperactivity disorder ( 32279069) Bipolar disorder ( 31043756) Malaria ( 31844061) Myeloproliferative neoplasms ( 33057200) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smooth-surface caries ( 24556642) Total cholesterol levels ( 30275531)	Age at first birth ( 34211149 27798627) Blood metabolite levels ( 26401656) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) General cognitive ability ( 29844566)
Interacting Genes		27 interacting genes: APP CDKN1B CSE1L CSNK2A1 CUL4B CYHR1 EXO1 FAM50B GTF2IRD1 HIF1A HNRNPC HSD3B7 KAT5 KPNB1 MAT2B MTA1 NCBP3 NFE2L2 NTRK3 NUP50 OGT PLAA RAC1 RCC1 RECQL TGM2 WT1	13 interacting genes: ALDH3A1 FXR1 HOXA1 KPNA3 KPNA4 KRTAP1-1 KRTAP1-3 LGALS3 MAPK9 NBPF19 NOTCH2NLA PVR SDCBP
Entrez ID		3840	50626
HPRD ID		04275	13107
Ensembl ID		ENSG00000186432	ENSG00000187954
Uniprot IDs		O00629	E9PJD7 Q6ZMK1
PDB IDs		4UAE 5TBK 5XZX 6BVV 6BVZ 6BW9 6BWA 6BWB 6WX8 7JJL
Enriched GO Terms of Interacting Partners?
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