KPNA4 and NCBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KPNA4	NCBP3
Description		karyopherin subunit alpha 4	nuclear cap binding subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Membrane	Nucleus Cytoplasm Nuclear Speck RNA Cap Binding Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus	7-methylguanosine MRNA Capping MRNA Transport Defense Response To Virus
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Attention deficit hyperactivity disorder ( 32279069) Bipolar disorder ( 31043756) Malaria ( 31844061) Myeloproliferative neoplasms ( 33057200) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smooth-surface caries ( 24556642) Total cholesterol levels ( 30275531)	Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		27 interacting genes: APP CDKN1B CSE1L CSNK2A1 CUL4B CYHR1 EXO1 FAM50B GTF2IRD1 HIF1A HNRNPC HSD3B7 KAT5 KPNB1 MAT2B MTA1 NCBP3 NFE2L2 NTRK3 NUP50 OGT PLAA RAC1 RCC1 RECQL TGM2 WT1	8 interacting genes: APP DAPK1 HMGB2 HNRNPH3 KPNA4 LENG8 LRRK2 SRPK2
Entrez ID		3840	55421
HPRD ID		04275	17116
Ensembl ID		ENSG00000186432	ENSG00000074356
Uniprot IDs		O00629	Q53F19
PDB IDs		4UAE 5TBK 5XZX 6BVV 6BVZ 6BW9 6BWA 6BWB 6WX8 7JJL
Enriched GO Terms of Interacting Partners?
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