P2RX7 and TM9SF1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		P2RX7	TM9SF1
Description		purinergic receptor P2X 7	transmembrane 9 superfamily member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Inner Membrane Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Bleb Postsynapse	Autophagosome Membrane Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Lipopolysaccharide Binding Purinergic Nucleotide Receptor Activity Extracellularly ATP-gated Cation Channel Activity Signaling Receptor Binding Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Regulation Of Sodium Ion Transport Response To Ischemia Cell Surface Receptor Signaling Pathway Positive Regulation Of Calcium Ion Transport Into Cytosol Positive Regulation Of Gene Expression Plasma Membrane Phospholipid Scrambling Sensory Perception Of Pain Positive Regulation Of Bone Mineralization Bleb Assembly Positive Regulation Of Interleukin-1 Beta Production Response To ATP Positive Regulation Of Ion Transmembrane Transport Calcium-mediated Signaling Using Extracellular Calcium Source Purinergic Nucleotide Receptor Signaling Pathway Negative Regulation Of MAPK Cascade Negative Regulation Of Bone Resorption Negative Regulation Of Cell Volume Positive Regulation Of Glycolytic Process Pore Complex Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Killing Of Cells Of Other Organism Membrane Depolarization Excitatory Postsynaptic Potential Calcium Ion Transmembrane Transport Cellular Response To ATP Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Bleb Assembly Cell Surface Receptor Signaling Pathway Involved In Cell-cell Signaling	Autophagy Protein Localization To Membrane
Pathways		Elevation of cytosolic Ca2+ levels Platelet homeostasis The NLRP3 inflammasome The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs		Promethazine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Birth weight ( 31043758) Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
Interacting Genes		20 interacting genes: ACTB CASK CSF2 CYSRT1 EFEMP2 EFNB3 EMP3 HSF2BP KRT31 KRT34 KRTAP10-8 NBPF19 NOTCH2NLA PANX1 PLEKHF2 PTPN11 SVIL TM9SF1 TRIM27 ZNF655	5 interacting genes: MTNR1A P2RX7 RNASEH1 TCOF1 ZBTB14
Entrez ID		5027	10548
HPRD ID		03977	09987
Ensembl ID		ENSG00000089041	ENSG00000100926
Uniprot IDs		Q99572	B4E3A9 G3V1B9 O15321
PDB IDs
Enriched GO Terms of Interacting Partners?
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