TRIM72 and NMI

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM72	NMI
Description		tripartite motif containing 72	N-myc and STAT interactor
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Vesicle Membrane Sarcolemma	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Phosphatidylserine Binding Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Transcription Coregulator Activity Protein Binding Identical Protein Binding
	Biological Process	Plasma Membrane Repair Muscle System Process Exocytosis Muscle Organ Development Negative Regulation Of Myotube Differentiation Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Protein Homooligomerization	Macrophage Activation Involved In Immune Response Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Interferon-gamma-mediated Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein K48-linked Ubiquitination
Pathways		Smooth Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS			Blood protein levels ( 28240269)
Interacting Genes		15 interacting genes: ABI2 C1orf216 INSR IRS1 MED21 MZT1 NMI PPP3CA SMARCD1 TCF12 TRIM32 UBE2I UBE2N VSIG4 ZNF655	60 interacting genes: BRAT1 BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EPC2 EXOSC5 GART GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		493829	9111
HPRD ID		17412	04632
Ensembl ID		ENSG00000177238	ENSG00000123609
Uniprot IDs		Q6ZMU5	Q13287
PDB IDs		3KB5
Enriched GO Terms of Interacting Partners?
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