NT5E and ZNRF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NT5E	ZNRF4
Description		5'-nucleotidase ecto	zinc and ring finger 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Protein Binding 5'-nucleotidase Activity Metal Ion Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	AMP Catabolic Process DNA Metabolic Process Leukocyte Cell-cell Adhesion Dephosphorylation ADP Catabolic Process Adenosine Biosynthetic Process Negative Regulation Of Inflammatory Response	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways		Nicotinate metabolism Pyrimidine catabolism Purine catabolism Purinergic signaling in leishmaniasis infection
Drugs		Pentoxifylline
Diseases
GWAS		Blood metabolite levels ( 24816252) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lung function ( 31902109) Metabolic traits ( 21886157) Serum metabolite levels ( 33031748)
Interacting Genes		7 interacting genes: ACTB AFF1 ATP6AP1 FN1 LAMA1 RNF24 ZNRF4	13 interacting genes: NT5E RIPK2 TPRX1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2G2 UBE2N UBE2W UPK2
Entrez ID		4907	148066
HPRD ID		00552	15895
Ensembl ID		ENSG00000135318	ENSG00000105428
Uniprot IDs		P21589 Q6NZX3	Q8WWF5
PDB IDs		4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I 6HXW 6S7F 6S7H 6TVE 6TVG 6TVX 6TW0 6TWA 6TWF 6XUE 6XUG 6XUQ 6YE1 6YE2 6Z9B 6Z9D 7JV8 7JV9
Enriched GO Terms of Interacting Partners?
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