ZNRF4 and NT5E

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNRF4	NT5E
Description		zinc and ring finger 4	5'-nucleotidase ecto
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleoplasm Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleotide Binding Protein Binding 5'-nucleotidase Activity Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	AMP Catabolic Process DNA Metabolic Process Leukocyte Cell-cell Adhesion Dephosphorylation ADP Catabolic Process Adenosine Biosynthetic Process Negative Regulation Of Inflammatory Response
Pathways			Nicotinate metabolism Pyrimidine catabolism Purine catabolism Purinergic signaling in leishmaniasis infection
Drugs			Pentoxifylline
Diseases
GWAS			Blood metabolite levels ( 24816252) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lung function ( 31902109) Metabolic traits ( 21886157) Serum metabolite levels ( 33031748)
Interacting Genes		13 interacting genes: NT5E RIPK2 TPRX1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2G2 UBE2N UBE2W UPK2	7 interacting genes: ACTB AFF1 ATP6AP1 FN1 LAMA1 RNF24 ZNRF4
Entrez ID		148066	4907
HPRD ID		15895	00552
Ensembl ID		ENSG00000105428	ENSG00000135318
Uniprot IDs		Q8WWF5	P21589 Q6NZX3
PDB IDs			4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I 6HXW 6S7F 6S7H 6TVE 6TVG 6TVX 6TW0 6TWA 6TWF 6XUE 6XUG 6XUQ 6YE1 6YE2 6Z9B 6Z9D 7JV8 7JV9
Enriched GO Terms of Interacting Partners?
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