NPHP1 and INVS

Number of citations of the paper that reports this interaction (PubMedID 12872123)
198

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		NPHP1	INVS
Description		nephrocystin 1	inversin
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Bicellular Tight Junction Cilium Membrane Motile Cilium Photoreceptor Connecting Cilium	Nucleus Cytoplasm Spindle Microtubule Cilium Membrane Ciliary Inversin Compartment
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Calmodulin Binding
	Biological Process	Signal Transduction Excretion Visual Behavior Cell Projection Organization Actin Cytoskeleton Organization Spermatid Differentiation Retina Development In Camera-type Eye Protein Localization Involved In Establishment Of Planar Polarity Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly	Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Protein Localization To Ciliary Inversin Compartment
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS			Macular thickness ( 30535121) Preeclampsia ( 23551011)
Interacting Genes		18 interacting genes: ADAM15 ARHGAP32 BCAR1 BCL2L11 COX5B FBXO7 FLNA FLNB FLNC INVS KHDRBS1 NPHP3 NPHP4 PAK2 PTK2B TNK2 TUBB UBQLN4	6 interacting genes: ABCA1 CALM2 HIF1AN NPHP1 TMEM245 ZNF512B
Entrez ID		4867	27130
HPRD ID		09524	08356
Ensembl ID		ENSG00000144061	ENSG00000119509
Uniprot IDs		C9JNM7 O15259	A0A024R153 Q2M1I4 Q9Y283
PDB IDs		1S1N 6O1Q
Enriched GO Terms of Interacting Partners?
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