NPHP1 and COX5B

		NPHP1	COX5B
Description		nephrocystin 1	cytochrome c oxidase subunit 5B
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Bicellular Tight Junction Cilium Membrane Motile Cilium Photoreceptor Connecting Cilium	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV
	Molecular Function	Structural Molecule Activity Protein Binding	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Excretion Visual Behavior Cell Projection Organization Actin Cytoskeleton Organization Spermatid Differentiation Retina Development In Camera-type Eye Protein Localization Involved In Establishment Of Planar Polarity Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly	Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Proton Transmembrane Transport
Pathways		Anchoring of the basal body to the plasma membrane	TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1
Drugs			Cholic Acid N-Formylmethionine
Diseases
GWAS			Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: ADAM15 ARHGAP32 BCAR1 BCL2L11 COX5B FBXO7 FLNA FLNB FLNC INVS KHDRBS1 NPHP3 NPHP4 PAK2 PTK2B TNK2 TUBB UBQLN4	36 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NPHP1 NUDT5 OIP5 PLEKHF2 PNMA1 PPP1R32 PRDM6 PRKAR1B PRR22 RBM48 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28
Entrez ID		4867	1329
HPRD ID		09524	00467
Ensembl ID		ENSG00000144061	ENSG00000135940
Uniprot IDs		C9JNM7 O15259	A0A384NL93 P10606
PDB IDs		1S1N 6O1Q	5Z62
Enriched GO Terms of Interacting Partners?
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