INVS and NPHP1

Number of citations of the paper that reports this interaction (PubMedID 12872123)
198

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		INVS	NPHP1
Description		inversin	nephrocystin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule Cilium Membrane Ciliary Inversin Compartment	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Bicellular Tight Junction Cilium Membrane Motile Cilium Photoreceptor Connecting Cilium
	Molecular Function	Protein Binding Calmodulin Binding	Structural Molecule Activity Protein Binding
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Protein Localization To Ciliary Inversin Compartment	Signal Transduction Excretion Visual Behavior Cell Projection Organization Actin Cytoskeleton Organization Spermatid Differentiation Retina Development In Camera-type Eye Protein Localization Involved In Establishment Of Planar Polarity Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Macular thickness ( 30535121) Preeclampsia ( 23551011)
Interacting Genes		6 interacting genes: ABCA1 CALM2 HIF1AN NPHP1 TMEM245 ZNF512B	18 interacting genes: ADAM15 ARHGAP32 BCAR1 BCL2L11 COX5B FBXO7 FLNA FLNB FLNC INVS KHDRBS1 NPHP3 NPHP4 PAK2 PTK2B TNK2 TUBB UBQLN4
Entrez ID		27130	4867
HPRD ID		08356	09524
Ensembl ID		ENSG00000119509	ENSG00000144061
Uniprot IDs		A0A024R153 Q2M1I4 Q9Y283	C9JNM7 O15259
PDB IDs			1S1N 6O1Q
Enriched GO Terms of Interacting Partners?
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