NINJ1 and FCGR1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NINJ1	FCGR1A
Description		ninjurin 1	Fc fragment of IgG receptor Ia
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Integral Component Of Membrane Synaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane Early Endosome Membrane
	Molecular Function	Lipopolysaccharide Binding Protein Binding Cell Adhesion Mediator Activity	Transmembrane Signaling Receptor Activity Protein Binding IgG Binding
	Biological Process	Angiogenesis Leukocyte Chemotaxis Involved In Inflammatory Response Cell Adhesion Nervous System Development Programmed Cell Death Cytolysis Heterotypic Cell-cell Adhesion Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Tissue Regeneration Muscle Cell Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Inflammatory Response Protein Homooligomerization Necrotic Cell Death	Phagocytosis, Engulfment Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Innate Immune Response Regulation Of Immune Response Positive Regulation Of Protein Tyrosine Kinase Activity
Pathways			Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes) Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis Interferon gamma signaling FCGR3A-mediated IL10 synthesis
Drugs			Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Alemtuzumab Natalizumab Palivizumab Daclizumab Bevacizumab Porfimer sodium Catumaxomab Sarilumab Trastuzumab deruxtecan
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Lactate dehydrogenase levels ( 29403010) Liver enzyme levels (alanine transaminase) ( 33972514) Obesity (early onset extreme) ( 23563609)
Interacting Genes		20 interacting genes: AQP6 CD200R1 CEACAM3 CREB3L1 CYB5R3 EBP FCGR1A FNDC9 GOLM1 GPX8 HIVEP1 KRT40 LIME1 MUC1 PVR SGCB TIMMDC1 TLCD4 TMEM14B TMEM31	30 interacting genes: ADIPOQ APCS ASGR1 BIK BMP10 CD163 CLDN19 CLEC7A CRKL CRP FAM3C FCAR FCGR3A HCK HRG ITM2A JAGN1 LAT LHFPL5 LILRB2 MALL NINJ1 NRSN1 RPRM SYK TNMD TSPO2 UPK2 VSTM1 VTI1B
Entrez ID		4814	2209
HPRD ID		03639	00904
Ensembl ID		ENSG00000131669	ENSG00000150337
Uniprot IDs		Q92982	P12314
PDB IDs			3RJD 4W4O 4X4M 4ZNE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?