FCGR1A and TNMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FCGR1A	TNMD
Description		Fc fragment of IgG receptor Ia	tenomodulin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane Early Endosome Membrane	Nuclear Envelope Cytoplasm Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding IgG Binding	Protein Binding
	Biological Process	Phagocytosis, Engulfment Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Innate Immune Response Regulation Of Immune Response Positive Regulation Of Protein Tyrosine Kinase Activity	Endothelial Cell Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Tendon Cell Differentiation Cellular Response To BMP Stimulus
Pathways		Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes) Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis Interferon gamma signaling FCGR3A-mediated IL10 synthesis
Drugs		Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Alemtuzumab Natalizumab Palivizumab Daclizumab Bevacizumab Porfimer sodium Catumaxomab Sarilumab Trastuzumab deruxtecan
Diseases
GWAS
Interacting Genes		30 interacting genes: ADIPOQ APCS ASGR1 BIK BMP10 CD163 CLDN19 CLEC7A CRKL CRP FAM3C FCAR FCGR3A HCK HRG ITM2A JAGN1 LAT LHFPL5 LILRB2 MALL NINJ1 NRSN1 RPRM SYK TNMD TSPO2 UPK2 VSTM1 VTI1B	17 interacting genes: AMIGO1 ARL13B BCL2L13 BNIP3 BNIP3L CD33 CREB3L1 FAM209A FCGR1A GGT6 HHLA2 KIR3DL3 LMNA MYG1 SPAG4 TMEM106A TMEM79
Entrez ID		2209	64102
HPRD ID		00904	02352
Ensembl ID		ENSG00000150337	ENSG00000000005
Uniprot IDs		P12314	Q9H2S6
PDB IDs		3RJD 4W4O 4X4M 4ZNE
Enriched GO Terms of Interacting Partners?
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