NEK1 and CFAP410

Number of citations of the paper that reports this interaction (PubMedID 32891887)
1

Data Source:
BioGRID (enzymatic study)

		NEK1	CFAP410
Description		NIMA related kinase 1	cilia and flagella associated protein 410
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Centriolar Satellite	Photoreceptor Outer Segment Cytoplasm Mitochondrion Cytosol Plasma Membrane Photoreceptor Connecting Cilium Ciliary Basal Body Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding 14-3-3 Protein Binding Protein Serine Kinase Activity	Molecular_function Protein Binding
	Biological Process	Protein Phosphorylation Cell Cycle Peptidyl-tyrosine Phosphorylation DNA Damage Response, Detection Of DNA Damage Cell Division Cilium Assembly	Cytoskeleton Organization Smoothened Signaling Pathway Regulation Of Cell Shape DNA Damage Response, Detection Of DNA Damage Cilium Assembly
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Daytime nap ( 33568662) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656) Supramarginal gyrus volume ( 31530798)
Interacting Genes		27 interacting genes: ANXA10 ATRX CFAP410 CLCN3 CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 GTF2H4 H2BC21 HAND2 HIP1R KIF3A LRRK1 LRRK2 MFHAS1 MRE11 PPP2R5A PTPRD RTN4R SIRPA TAF9 TP53BP1 TSC2 YWHAH ZNF350	7 interacting genes: ATOX1 COL6A1 DOP1B FBXO3 GMCL1 NEK1 SPG21
Entrez ID		4750	755
HPRD ID		06847	04427
Ensembl ID		ENSG00000137601	ENSG00000160226
Uniprot IDs		Q5JXL9 Q96PY6	O43822
PDB IDs		4APC 4B9D
Enriched GO Terms of Interacting Partners?
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