MEOX1 and NAGK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MEOX1	NAGK
Description		mesenchyme homeobox 1	N-acetylglucosamine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity
	Biological Process	Somite Specification Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation
Pathways			Synthesis of UDP-N-acetyl-glucosamine
Drugs			N-Acetylglucosamine
Diseases
GWAS		Fractures ( 30158200)	Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		99 interacting genes: ACBD4 ACOT12 ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf109 C1orf50 C2CD6 CACNB3 CCDC102B CCDC103 CDC34 CIAO1 CIB3 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DUSP3 EIF4A3 EIF4EBP1 EMD FAM126B FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TEX33 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410	34 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 ELP4 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82
Entrez ID		4222	55577
HPRD ID		02537	08441
Ensembl ID		ENSG00000005102	ENSG00000124357
Uniprot IDs		P50221	A0A384N6G7 C9JEV6 Q9UJ70
PDB IDs			2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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