LIMS1 and USP11

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		LIMS1	USP11
Description		LIM zinc finger domain containing 1	ubiquitin specific peptidase 11
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Protein Kinase Binding Protein-containing Complex Binding	Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination
Pathways		Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		48 interacting genes: ADAMTS9 ATXN10 CATSPER1 CCN2 COL8A1 CSRP3 CWF19L2 DAPK1 EHMT2 FAM90A1 FERMT2 FERMT3 FMR1 GEM ILK INO80B IPO7 KAT8 KPRP LMO3 LPXN MBIP MYO15B NCK2 NEB OSR2 PARVA PEG3 PLCE1 RAD51D RBBP8 RSU1 SCNM1 SMURF1 TBC1D22B TCEA2 TGFBR1 TMSB4X TRIO TTN USP11 ZIM2 ZMYM4 ZNF160 ZNF410 ZNF417 ZNF564 ZNF587	22 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 NONO PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC
Entrez ID		3987	8237
HPRD ID		03978	02081
Ensembl ID		ENSG00000169756	ENSG00000102226
Uniprot IDs		P48059	B4DGK3 P51784
PDB IDs		1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF 7D2S 7D2T 7D2U	4MEL 5OK6
Enriched GO Terms of Interacting Partners?
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